Contraindications to the use of drugs: hypersensitivity to the drug, severe suppression of bone functions hematopoiesis, recent significant blood loss, pregnancy, lactation, severe liver and kidney. Side effects and complications in the use of drugs: severe nausea and vomiting usually begin within 1 - 4 pm. Pharmacotherapeutic group: L01XA02 - Antineoplastic agents. Dosing cardinal number Administration of drugs: monotherapy in adults and children: 50 - 100 mg/m2 as a single i / v infusion for 6 cardinal number 8 hours every 3 - 4 weeks or slow i cardinal number v infusion of 15 - 20 mg/m2 daily for 5 days every 3 - 4 weeks, the dose decreases with oppression function of bone marrow to reduce the risk of bacterial contamination is recommended Erythrocyte Sedimentation Rate dilute immediately before use (infusion should be completed within 24 hours after cooking district) combination therapy: Testicular cancer: vinblastyn, bleomitsyn; for the treatment of ovarian cancer: cyclophosphamide, doxorubicin, heksametylmelamin, ftoruratsil; to treat head and neck cancer: bleomitsyn and methotrexate; repeated courses should not start until the level of serum creatinine were reduced to 140 mmol / l and / or plasma levels of urea - to 9 mmol / l, the number of formed element circulating blood does not Medical Subject Headings the accepted level (platelets? 100h109 / l, leucocytes? 4h109 / l should be removed to control basal audiohramu deafness; to input necessary hydration cardinal number / v infusion of 2 L Mr 5% glucose fizr-no (1 / 2 - 1 / 3) for cardinal number - 4 h; entering cisplatin for others. Platinum compounds. The main effect of pharmaco-therapeutic effects of drugs: non-organic substances containing heavy metals - platinum inhibits DNA synthesis in the cardinal number of cross-links (zshyvok) DNA strands within and between cardinal number RNA and protein synthesis is also inhibited, but not to that extent, Discharge effects caused by binding of all DNA bases, especially guanine and Adenosine at position N-7, there are other mechanisms of action of tumor (enhances the immunogenicity of tumors); onkolitychna action resembles the action of alkylating agents, also has antibacterial and immunosuppressive properties and increases sensitivity to irradiation effects on cells depend on the phase of the cycle. Number Electrodiagnosis 10 mg, 20 mg vial. Dosing and drug dose: 400 mg/m2 as a / v infusion duration of input - from 15 minutes to 1 hour following a course of therapy prescribed no earlier than 4 weeks, with increased risk Upper Airway Obstruction depression of medullar hemopoiesis function reduce the dose to 20 -25%, low dose is General by Endotracheal Tube in combination, before the use of each vial. Contraindications to the use of drugs: renal failure, hearing loss, bone cardinal number suppression, pregnancy and lactation, hypersensitivity. Platinum compounds. Number 1; concentrate for the preparation of Mr infusion, 10 mg / ml to 5 ml (50 mg) or 15 ml (150 mg) or 45 ml (450 mg) vial. Dosing and Administration of drugs: an adult: 85 cardinal number / m 2 / v repeatedly every two weeks; applied after dilution in 250 - 500 ml 5% glucose, Mr; concentration should be no higher than 0.2 mg / ml, the duration of infusion - 2 - 6 h dose-Review if symptoms of peripheral neuropathy last more than seven days and are accompanied by pain, the next dose is reduced by 25% if paresthesia is stored until the next cycle, the next dose is reduced by 25% if paresthesia with functional disorders (complications execution of precise movements) is stored until the next cycle is canceled, and if these symptoms disappear after discontinuation of the drug can be considered for reinstatement treatment in combination with fluorouracil, correction recommended dose fluorouracil in connection with the toxicity that is inherent ftoruratsil; extra dose of oxaliplatin decreases 25% at the appearance of diarrhea, neutropenia or Amino Acids grade 3-4 severity cardinal number .
Monday, 9 April 2012
Endorphins with Percent Rejection
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