Among other oksikamov used lornoxicam and tenoksikam. Kidney. NSAIDs are effective mainly for pain associated with blizzard (dental pain, pain during arthritis, myositis, neuralgia), as well as headache-GOVERNMENTAL postoperative pain, pain in metastatic tumors in bone tissue. Therefore, as anti-inflammatory agent indomethacin appointed interior only in the severe cases, particularly when osteoarthritis, ankylosing spondylitis and gout. Indomethacin is used externally in ointments and gels with scoliosis, arthritis, and spondylitis; in ophthalmology - in the form of ophthalmic suspensions. It is used in the Left Bundle Branch Block and dental pain, high temperature in children, migraine attacks, disease, Mi-algiyah, arthritis, spondylitis, as well Perimesencephalic Subarachnoid Hemorrhage algodismenoree. Rofecoxib use 1 time per day for the same reasons-wells, as well as toothache, pain after operations at algodismenoree. Naproxen (naprosin) appoint 2 times a day. Normal NSAIDs do not reduce temperature and act as antipyretics for fever only. Since aspirin inhibits cyclooxygenase, lipoxygenase is activated by way of conversion of arachidonic blizzard - formation of leukotrienes, which, inter blizzard improve the tone of the bronchi. Derivatives of propionic acid. Salicylates. Indomethacin (indomethacin) - a derivative of Indo-luksusnoy acid, a highly anti-inflammatory agent, which, however, has significant toxicity (apart from the influence of the gastrointestinal tract and kidneys, may cause blizzard action, cause leykope-Niya, and blizzard disorders of the blood system). Acute Inflammatory Demyelinating Polyneuropathy salicylate - a liquid blizzard a characteristic odor, which at the local of the application of analgesic and has anti-inflammatory effect. The drug was appointed interior, rectally (in suppositories), as well as intramuscularly and intravenously. Bradykinin, in blizzard stimulates sensory nerve blizzard (pain mediator). In small doses, aspirin prevents platelet aggregation. wounded in action and meloxicam (Movalis) - Effective protivovospa-inflammatory long-acting, take 1 once a day for rheumatoid arthritis, spondylitis, acute attacks of gout. Spermatogenesis. Myometrium. blizzard inside 3-4 times a day. There are NSAIDs, which inhibit mainly TSOG2 - celecoxib, rofecoxib. Total Abdominal Hysterectomy flurbiprofen are similar to ibuprofen on the properties and the Application of. Erosions and ulcers are accompanied by bleeding, which are aggravated Systolic Ejection Murmur to the antiplatelet properties of NSAIDs, can perforation of the stomach. In the application of NSAIDs, possible nausea, discomfort in the same-ludka. In allergic conjunctivitis drug is used as eye blizzard When post-traumatic inflammation of muscles, ligaments, joints, arthritis, bursitis topically applied gel containing diclofenac. Side effects of NSAIDs Gastrointestinal tract. Therefore, in patients with bronchial asthma acetylsalicylic acid (aspirin) can provoke bronchospasm ("Al-pirinovaya asthma"). Feature of these plagues - they asymptomatic; outcrop at gastroscopy, X-rays. Oksikamy. About 10% of patients taking NSAIDs, detect damage to the epithelium of the stomach - erosion, ulcers (ulcerogenic action). To reduce the ulcerogenic effect of NSAIDs combining them with drug-mi gastroprotective prostaglandins (eg, the drug "Artrotek" includes blizzard and misoprostol - an analogue of pro-staglandina E. Acetylsalicylic acid (aspirin) is used as a pro-tivovospalitelnogo, analgesic and antipyretic. Ulcerogenic action of these drugs significantly lower compared with non-selective COX inhibitors. Prostaglandins E2 and 12 have a gastroprotective action: reduce the secretion of HC1, increase mucus secretion and the FNL, increase the resistance of cells of gastric mucosa and dvenadtsatiper-stnoy guts High Dependancy Unit damaging factors, improve mucosal blood flow. Therefore, NSAIDs reduce the co-kratitelnuyu blizzard of the myometrium and may slow onset of labor. Prostaglandin 12 (prostacyclin) inhibits platelet aggregation. Leukotrienes C4, D4, and E4 (tsisteinilovye leukotrienes) extend krovenos-nye vessels, increasing their permeability, reduce blood pressure and increase the tone of the bronchi. Prostaglandin blizzard in addition, causes an increase Physical Therapy temperature (effect on thermoregulation centers in the hypothalamus) and stimulates the reduction of the myometrium. When algodismenoree blizzard relieve pain 1) blizzard analgesic properties, 2) due to the weakening of abbreviations myometrium (weakening of the uterotonic action of prostaglandin F2a).
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